منابع مشابه
Chromosome dynamics: Yeast pulls it apart
Sister chromatid cohesion and chromosome condensation are both essential to the successful completion of mitosis. The recent identification and characterization of the yeast Mcd1p/Scc1p protein reveals a previously unsuspected mechanistic link between these processes.
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N otch's neighbors are tearing it apart. On page 445, Nichols et al. show that endocytosis of a ligand on one cell pulls apart its Notch receptor on an adjacent cell, leaving behind an activation-susceptible receptor remnant. Dormant Notch on the cell surface must be cleaved into a free intra-cellular domain that can travel to the nucleus to activate gene expression. Three proteases are known t...
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The ParM ATPase from Escherichia coli plasmid R1 assembles into F-actin-like filaments which appear to push replicated copies of the plasmid to opposite ends of the cell, ensuring partitioning into daughter cells. Might bacterial chromosomes use a similar mitotic strategy for segregation?
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In an alternative mode, the Sec61 protein associates with a tetrameric Sec62/63p complex to form the SEC complex, a channel active in posttranslational transloca-heat shock 70 protein (Hsp70) called BiP, or Kar2p in yeast (Lyman and Schekman, 1997). BiP and the SEC complex are the only components required for translo-cation in a reconstituted system (Panzner et al., 1995); of A significant frac...
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Social competition is a fundamental mechanism of evolution and plays a central role in structuring individual interactions and communities. Little is known about the factors that affect individuals' competitive success, particularly in humans. Key factors might include stress, a major evolutionary pressure that can affect the establishment of social hierarchies in animals, and individuals' trai...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1998
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(98)70050-8